Key Takeaways
- Cooking Time: Cook turkey tenderloin at 400°F for approximately 20 to 25 minutes per pound, resulting in a total cooking time of 30 to 50 minutes for the average 1.5 to 2-pound tenderloin.
- Safe Internal Temperature: Ensure the internal temperature reaches 165°F, verified with a meat thermometer inserted into the thickest part of the tenderloin.
- Marinating Benefits: Marinate the tenderloin for at least 30 minutes to overnight to enhance flavor and moisture; effective marinades include olive oil, garlic, herbs, and citrus juices.
- Oven Preparation: Preheat your oven to 400°F, use a well-greased baking dish, and position the tenderloin in the center for even cooking.
- Factors Influencing Cooking Time: Be aware that size, oven calibration, starting temperature, and any added toppings or stuffing can affect overall cooking time.
- Signs of Doneness: Look for clear juices, a firm yet slightly springy texture, and a light golden brown color to confirm the turkey’s doneness along with the thermometer reading.
Wondering how long to cook turkey tenderloin in the oven at 400 degrees? You’re not alone. Many home cooks face the challenge of getting that perfect balance between juicy and fully cooked, especially when it comes to turkey.
Overview of Turkey Tenderloin
Turkey tenderloin is a lean cut from the breast of the turkey. It’s known for its mild flavor and tender texture, making it a versatile option for various dishes. Typically, a turkey tenderloin weighs between 1.5 to 2 pounds and is ideal for roasting, grilling, or sautéing.
When cooking turkey tenderloin, pay attention to cooking times and temperatures to ensure optimal flavor and doneness. At 400 degrees Fahrenheit, a general rule is to cook turkey tenderloin for 20 to 25 minutes per pound. This timing helps keep the meat juicy while ensuring thorough cooking.
Using a meat thermometer is essential. Aim for an internal temperature of 165 degrees Fahrenheit to guarantee safety and tenderness. Insert the thermometer into the thickest part of the tenderloin for the most accurate reading.





Marinating or brining the tenderloin before cooking can enhance its flavor and moisture. Common ingredients for marinades include olive oil, garlic, herbs, and citrus juices. Allow the turkey to marinate for at least 30 minutes or up to overnight for the best results.
Preparing side dishes to accompany your turkey tenderloin can elevate your meal. Roasted vegetables, mashed potatoes, or a fresh salad complement the dish nicely. Preparing sides ahead of time helps streamline your cooking process.
By focusing on these factors, you can confidently overcome the challenges of cooking turkey tenderloin, achieving a delicious and satisfying result.
Cooking Turkey Tenderloin at 400 Degrees
Cooking turkey tenderloin at 400 degrees Fahrenheit requires attention to both time and temperature. This optimal temperature helps achieve a beautifully cooked, juicy tenderloin.
Recommended Cooking Time
For turkey tenderloin, the recommended cooking time is 20 to 25 minutes per pound. Since most tenderloins weigh between 1.5 to 2 pounds, you should expect a cooking time of approximately 30 to 50 minutes. It’s crucial to monitor the internal temperature, which must reach 165 degrees Fahrenheit for safety. Using a meat thermometer allows for accuracy; insert it into the thickest part of the tenderloin for the best results.
Factors Affecting Cooking Time
Several factors can influence the cooking time of turkey tenderloin:
- Size and Thickness: Larger or thicker tenderloins take longer to cook.
- Oven Calibration: Your oven’s temperature accuracy can affect cooking time. Using an oven thermometer ensures you cook at the right temperature.
- Starting Temperature: Cooking turkey tenderloin straight from the refrigerator may require additional time. Letting it sit at room temperature for about 30 minutes before cooking can help.
- Stuffing or Toppings: If you add stuffing or a thick layer of sauce, cooking time can increase.
By understanding these factors, you can adjust cooking times for perfectly tender and juicy turkey every time.





Preparing Turkey Tenderloin for Cooking
Preparing turkey tenderloin properly ensures a delicious and juicy result. Focus on marinating, seasoning, and correctly setting up your oven and cookware for the best cooking experience.
Marinating and Seasoning
Marinating enhances the flavor and moisture of turkey tenderloin. Use a simple marinade to soak the meat for at least one hour, or preferably overnight. Ingredients like olive oil, garlic, herbs, and citrus juices work well.
- Choose Your Ingredients: Select a base like olive oil, then add flavor elements such as minced garlic and fresh herbs.
- Mix and Coat: Combine the marinade and coat the turkey tenderloin evenly. Seal it in a bag or container for the best infusion.
- Refrigerate: Store in the fridge while marinating. This allows the flavors to penetrate the meat effectively.
For seasoning, you can use salt and pepper or create a blend with your favorite spices. Apply seasoning just before cooking to maximize flavor.
Prepping the Oven and Cookware
Proper oven and cookware preparation contributes significantly to cooking success. Follow these steps to ensure your environment is ready:
- Preheat the Oven: Set your oven to 400 degrees Fahrenheit. Preheating ensures even cooking throughout.
- Select the Right Bakeware: Use a baking dish or oven-safe pan that accommodates the tenderloin comfortably. A shallow dish promotes better air circulation.
- Grease the Cookware: Lightly grease the bottom of your cookware with oil or cooking spray to prevent sticking.
- Positioning: Place the tenderloin in the center of the oven for optimal heat distribution. Avoid overcrowding to allow even cooking.
Taking these steps prepares your turkey tenderloin to cook evenly, ensuring it remains moist and flavorful.
Monitoring the Cooking Process
Monitoring the cooking process is crucial for achieving juicy, tender turkey tenderloin. Keep a close eye on the meat as it cooks to ensure perfect results.
Using a Meat Thermometer
Using a meat thermometer ensures you cook the tenderloin to the right temperature. Insert the thermometer into the thickest part of the meat, avoiding any bone. The ideal internal temperature for turkey tenderloin is 165 degrees Fahrenheit. This temperature guarantees safety and optimal juiciness. If the thermometer reads below this temperature, allow additional cooking time and check again after a few minutes.
Checking for Doneness
Checking for doneness involves more than just relying on cooking times. While cooking turkey tenderloin at 400 degrees Fahrenheit generally requires 20 to 25 minutes per pound, various factors may influence actual cook time. Look for the following signs of doneness:





- Juices: Juices should run clear, not pink when pierced.
- Texture: The meat should feel firm yet slightly springy.
- Color: The surface should have a light golden brown color.
Using these indicators alongside a meat thermometer helps confirm the turkey’s doneness, ensuring you serve a succulent dish every time.
Conclusion
Cooking turkey tenderloin at 400 degrees can lead to a deliciously juicy meal when you get the timing right. Remember to keep an eye on the internal temperature and aim for that magic number of 165 degrees.
Don’t forget that marinating can make a big difference in flavor and moisture. With a little attention to detail and the right cooking time, you’ll impress your family and friends with a perfectly cooked turkey tenderloin.
Enjoy your cooking adventure and savor every bite!
Frequently Asked Questions
How long do I cook turkey tenderloin at 400 degrees Fahrenheit?
To cook turkey tenderloin at 400 degrees Fahrenheit, aim for 20 to 25 minutes per pound. This typically results in a cooking time of about 30 to 50 minutes for most tenderloins. Always check the internal temperature for safety.
What is the ideal internal temperature for turkey tenderloin?
The ideal internal temperature for turkey tenderloin is 165 degrees Fahrenheit. Using a meat thermometer is essential to ensure the turkey is both safe to eat and remains tender and juicy.
Should I marinate turkey tenderloin before cooking?
Yes, marinating turkey tenderloin is recommended. Marinating for at least one hour or ideally overnight enhances flavor and moisture, making the meat much more delicious.
What affects the cooking time of turkey tenderloin?
Cooking time can be affected by factors such as the size and thickness of the tenderloin, your oven’s calibration, the starting temperature of the meat, and any added toppings or stuffing.
How do I know when turkey tenderloin is done?
In addition to using a meat thermometer, check for clear juices, a firm texture, and a light golden brown color. These indicators, combined with the correct internal temperature, confirm doneness.
What are good side dishes for turkey tenderloin?
Great side dishes for turkey tenderloin include roasted vegetables, mashed potatoes, or a fresh salad. These complement the mild flavor of the turkey and enhance your meal experience.